Autoimmunity Is Seen as the biggest unmet medical need on a global scale
Autoimmune diseases arise when immune regulation fails and control is lost: The immune system escapes its restraints and goes into overdrive, mounting an attack on the body’s own cells and tissues. The resulting chronic pathological inflammation causes lifelong suffering and significant loss of quality of life, with no cure in sight.
Current treatments address symptoms and act through suppression of the immune response; they are frequently associated with unpredictable and severe side effects, and may lose their efficacy due to acquired resistance.
There is a growing recognition that the key to treating autoimmune disease lies in rectifying the dysregulation and reinstatement of control rather than in combating the attack on the body.
Modern Diseases of Modern Times
- Autoimmune diseases are associated with industrialization and Westernization of society.
- Autoimmune diseases are multi-factorial, triggered by immune system dysregulations and imbalances; a potentially curative therapy is also multi factorial, restoring regulatory control.
- Inflammatory autoimmune conditions are the next Therapeutic Frontier